Iowa State University Athletics
1921 Football Schedule
Overall4-40.500
Conference3-40.429
StreakL1
Home3-2
Away1-2
Neutral0-0
| Date | Time | At | Opponent | Location | Tournament | Result |
|---|---|---|---|---|---|---|
| Oct 1 (Sat) | TBA | Home | Coe College | Ames, Iowa | W 28-3 | |
| Oct 8 (Sat) | TBA | Home | Grinnell College | Ames, Iowa | W 21-3 | |
| Oct 15 (Sat) | TBA | Away | Missouri | Columbia, Mo. | L 14-17 | |
| Oct 22 (Sat) | TBA | Home | Kansas | Ames, Iowa | L 7-14 | |
| Oct 29 (Sat) | TBA | Away | Washington University St. Louis | St. Louis, Mo. | L 0-2 | |
| Nov 5 (Sat) | TBA | Away | Drake | Des Moines, Iowa | W 7-0 | |
| Nov 11 (Fri) | TBA | Home | Kansas State | Ames, Iowa | W 7-0 | |
| Nov 19 (Sat) | TBA | Home | Nebraska | Ames, Iowa | L 3-35 |